Home Products ELISA Residue Kits Drugs of Abuse Ketamine (specific for norketamine)

Ketamine ELISA

Cat. No: KT3459 (Click Here to Order)

Overview

Key Advantages:

  • User friendly kit format
  • Exceptional Limits of detection
  • Plates pre-coated with analyte specific antibody, reducing assay set up time
  • Detects Norketamine and Dehydronorketamine in addition to Ketamine

This ELISA aims to give a fast, reliable, analytical method to detect the presence of ketamine. Ketamine was first synthesized in 1962 and subsequently marketed as an anaesthetic drug for human and animal use.It is a dissociative medical anaesthetic agent possessing hallucinogenic properties.

Ketamine became a drug of abuse shortly after it was introduced to clinical use. It has a very short half-life and rapid clearance from the body. It has been postulated that Ketamine is metabolised by N-demethylation, to yield the active metabolite norketamine, which is then followed by a hydroxylation process yielding hydroxyl-norketamine (HNK). The HNK can then undergo glucuronidation conjugation. It is thought that the norketamine can undergo dehydrogenation to yield dehydronorketamine.

Limit of Detection (LOD)

Equine Urine 4.54 ng/ml

Assay Specificity

Compound %Cross-Reactivity
Norketamine 100
Ketamine 2.89
Dehydronorketamine 4.47