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Beta-agonist ELISA

Catalogue No: SU2148 (Click Here to Order)

Overview

Key Advantages:

  • Generic Antibody - detects 12 beta agonist compounds
  • Rapid and simple assay format
  • Plates precoated with analyte specific antibody, reducing assay set up time.
  • Exceptional Limits of Detection
  • Accessory Immunoaffinity Columns available for sample clean up allowing higher signal to noise ratios and cleaner samples suitable for ELISA, HPLC or GC-MS
  • Methodologies developed for a range of sample matrices

Beta-agonists have chemical structures, similar to the naturally occurring catecholamines, adrenaline and noradrenaline. They were originally produced for the treatment of respiratory diseases such as asthma. Beta-agonists facilitate the use of fats rather than glucose as a fuel source.

Therefore, meat production is increased while fat deposition is inhibited. This improves the meat: fat ratio of animals and leads to the production of higher quality meat at lower cost. There is a risk that residues of Beta-agonists may be present in meat products, which may be harmful to the consumer. The use of Beta-agonists as growth promoters has been banned in most countries. Consequently, it is important that abuse of these compounds is monitored.

Assay Limits of Detection

urine 0.3ng/ml
serum 0.25ng/ml
tissue 0.25ng/g
feed 5ng/g
hair / feather 1ng/g
milk 0.2ng/ml
milk powder 0.2ng/ml

Assay Specificity

Beta-agonist % Cross-Reactivity 100% Clenbuterol % Cross-Reactivity 100% Salbutamol
Clenbuterol 100 116
Cimbuterol 112 130
Bromochlorbuterol 91 106
Carbuterol 90 105
Salbutamol 86 100
Methyl-Clenbuterol 75 87
Clenpenterol hydrochloride 65 76
Brombuterol 53 61
Terbutaline 50 58
Mabuterol 45 52
Mapenterol 32 37
Pirbuterol 25 29
Cimaterol 10 12
Clenproperol 9 11
Ractopamine < 0.2 <0.2
Feneterol < 0.2 <0.2
Clorprenaline 1 1.2
Penbutolol 48 56
Tulobuterol 23 27

Used in conjunction with Clenbuterol/b-Agonist Immunoaffinity Column and Clenbuterol Urine Controls